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[Effect of glucagon-like peptide 1 receptor agonists on body fat redistribution and muscle mass in overweight and obese type 2 diabetic patients]

The peptide also stimulates collagen and elastin production, enhances fibroblast activity, and promotes organized tissue remodeling

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Annu Rev Neurosci

30 In adolescents with obesity, semaglutide 2.4 mg once weekly led to weight loss similar to that observed in adults (a 16.1% mean reduction in BMI from baseline vs 0.6% with placebo at 68 weeks), along with improvements in cardiometabolic risk factors such as waist circumference, glycated haemoglobin (HbA 1c ), LDL-cholesterol, triglyceride and alanine transaminase levels